Tuesday, November 20, 2007

Anti-anaphylaxis pill?

The prospect of a pill that could cut the risk that a child with peanut allergy is killed by an extreme allergic response is raised today.

[...]

Now Dr Kirk Druey of the National Institute of Allergy and Infectious Diseases, Bethesda, and colleagues report that they have found a protein that suppresses anaphylactic shock, when an allergic response triggers a quick release of substances from special immune cells found in tissues, called mast cells, that can lead to these deadly effects.

Dr Druey said this find will provide basic insights into how to damp down this deadly response, by gene therapy or a small drug molecule to mimic the effects of this protein. However, he emphasised that, though potentially significant, it would take some years to do.

Telegraph.co.uk

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